All the research
Long Covid Learning collects research from scientists worldwide and summarizes the findings to make takeaways more accessible to those outside the research community. Study summaries can be shared as links or images in messages and social media.
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Risk remains after vaccines
This study selected a predominantly healthy, younger adult population and used a limited survey-based methodology. For this population it reported that receiving two doses of a Covid vaccine at least two weeks before infection lowered the risk of Long Covid symptoms 12 weeks later by 41%. The risk of those symptoms being severe enough to limit daily activity dropped by 37%. While this study shows that significant risk of Long Covid remains after vaccination, additional studies are needed to confirm how much vaccines reduce this risk.
⚠️ This study selected a predominantly healthy, younger adult population and used a limited survey-based methodology.
For this population it reported that receiving two doses of a Covid vaccine at least two weeks before infection lowered the risk of Long Covid symptoms 12 weeks later by 41%.
The risk of those symptoms being severe enough to limit daily activity dropped by 37%. While this study shows that significant risk of Long Covid remains after vaccination, additional studies are needed to confirm how much vaccines reduce this risk.
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48% affected 6-18 months later
48% of those in a population-level study reported persistent symptoms, impaired daily activities, and reduced health-related quality of life in the 6-18 months after Covid infection across sociodemographic factors and pre-existing health conditions. 1 in 20 had not recovered at all and 1 in 9 had worsening symptoms over the course of the study. Being vaccinated before infection reduced the risk of 7 of the 26 symptoms evaluated by 25-40%.
48% of those in a population-level study reported persistent symptoms, impaired daily activities, and reduced health-related quality of life in the 6-18 months after Covid infection across sociodemographic factors and pre-existing health conditions.
1 in 20 had not recovered at all and 1 in 9 had worsening symptoms over the course of the study. Being vaccinated before infection reduced the risk of 7 of the 26 symptoms evaluated by 25-40%.
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Risk remains after vaccines
Vaccines offer only limited protection against a few Long Covid consequences, reducing risk by less than 30%. The chances of most consequences are reduced only marginally — or not at all. Risks of all Long Covid symptoms together, as well as new cognitive symptoms, heart problems, kidney disease, liver disease, sleep disorders, abnormal breathing, diabetes, obesity, chest pain, joint pain, hypertension, abdominal pain, anxiety, depression, headache, and other symptoms did not differ between those with and without prior vaccination.
Vaccines offer only limited protection against a few Long Covid consequences, reducing risk by less than 30%. The chances of most consequences are reduced only marginally — or not at all.
Risks of all Long Covid symptoms together, as well as new cognitive symptoms, heart problems, kidney disease, liver disease, sleep disorders, abnormal breathing, diabetes, obesity, chest pain, joint pain, hypertension, abdominal pain, anxiety, depression, headache, and other symptoms did not differ between those with and without prior vaccination.
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Vaccines lower risk only 15%
Vaccination reduces the risk of death by 34% and Long Covid chronic health issues by only 15% in the six months following Covid infection. These risks were 50-75% higher than for those without evidence of infection. Risk reduction was most evident for blood clots (56%) and lung issues (46%), but modest in other organ systems. Long Covid symptoms are similar regardless of vaccination.
Vaccination reduces the risk of death by 34% and Long Covid chronic health issues by only 15% in the six months following Covid infection.
These risks were 50-75% higher than for those without evidence of infection. Risk reduction was most evident for blood clots (56%) and lung issues (46%), but modest in other organ systems. Long Covid symptoms are similar regardless of vaccination.
Source: Long COVID after breakthrough SARS-CoV-2 infection | Nature Medicine
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