Disrupted T cells and cortisol
Those suffering from Long Covid show "uniformly low" levels of cortisol, the body's main stress hormone that controls how the body makes and uses energy, sleep/wake cycles, blood pressure, and more.
Long Covid sufferers also had fewer memory immune T cells and more "exhausted" T cells, which play important roles in how the body fights disease (including the dormant diseases that Covid can reactivate).
Source: Distinguishing features of Long COVID identified through immune profiling | medRxiv
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