All the research
Long Covid Learning collects research from scientists worldwide and summarizes the findings to make takeaways more accessible to those outside the research community. Study summaries can be shared as links or images in messages and social media.
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Persistent systemic infection for months
In people who died of Covid, the virus was found in various tissues throughout the body, including the brain, as late as 230 days following the symptom onset of an acute infection. In some patients, the virus can cause systemic infection and persist in the body for months. Among the other affected organs and tissues are the heart and blood vessels, lungs and the respiratory system, muscles, skin, thyroid, esophagus, spleen, appendix, adrenal glands, ovaries, testes, and womb.
In people who died of Covid, the virus was found in various tissues throughout the body, including the brain, as late as 230 days following the symptom onset of an acute infection.
In some patients, the virus can cause systemic infection and persist in the body for months. Among the other affected organs and tissues are the heart and blood vessels, lungs and the respiratory system, muscles, skin, thyroid, esophagus, spleen, appendix, adrenal glands, ovaries, testes, and womb.
Source: SARS-CoV-2 infection and persistence in the human body and brain at autopsy | Nature
Insulin resistance and diabetes
Even those without a prior history of diabetes demonstrate abnormal insulin resistance and glycemic abnormalities 2 months after infection. Even a mild Covid infection is associated with 28% higher risk of developing type 2 diabetes in the year after initial infection. This suggests the need for diabetes screening even after mild Covid cases.
Even those without a prior history of diabetes demonstrate abnormal insulin resistance and glycemic abnormalities 2 months after infection.
Even a mild Covid infection is associated with 28% higher risk of developing type 2 diabetes in the year after initial infection.
This suggests the need for diabetes screening even after mild Covid cases.
Sources: Incidence of newly diagnosed diabetes after Covid-19 | SpringerLink and Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection | Nature Metabolism
Serious conditions in kids
After Covid infection, children have twice the risk of acute pulmonary embolisms (blood clots that move to the lungs), venous thromboembolic events (clotting in veins), and myocarditis or cardiomyopathy (inflammation of the heart). Rates of sudden kidney failure and type 1 diabetes are 20-30% higher.
After Covid infection, children have twice the risk of acute pulmonary embolisms (clots moving to the lungs), venous thromboembolic events (clotting in veins), and myocarditis or cardiomyopathy (inflammation of the heart).
Rates of sudden kidney failure and type 1 diabetes are 20-30% higher.
Disrupted T cells and cortisol
Those suffering from Long Covid show "uniformly low" levels of cortisol, the body's main stress hormone that controls how the body makes and uses energy, sleep/wake cycles, blood pressure, and more. Long Covid sufferers also had fewer memory immune T cells and more "exhausted" T cells, which play important roles in how the body fights disease (including the dormant diseases that Covid can reactivate).
Those suffering from Long Covid show "uniformly low" levels of cortisol, the body's main stress hormone that controls how the body makes and uses energy, sleep/wake cycles, blood pressure, and more.
Long Covid sufferers also had fewer memory immune T cells and more "exhausted" T cells, which play important roles in how the body fights disease (including the dormant diseases that Covid can reactivate).
Source: Distinguishing features of Long COVID identified through immune profiling | medRxiv