All the research

Long Covid Learning collects research from scientists worldwide and summarizes the findings to make takeaways more accessible to those outside the research community. Study summaries can be shared as links or images in messages and social media.

Visit “The Research” to navigate by topic or to search by keyword.

Immune system Greg Howard Immune system Greg Howard

Damaged immune system

SARS-CoV-2 directly infects and kills immune cells (lymphocytes), reducing the body's ability to fight Covid and increasing the severity of future infections — both future Covid variants and other diseases. The infection of cells not only impairs the body's immune response, they may aggravate the infection by carrying the virus to other parts of the body through the bloodstream.

SARS-CoV-2 directly infects and kills immune cells (lymphocytes), reducing the body's ability to fight Covid and increasing the severity of future infections — both future Covid variants and other diseases.

The infection of cells not only impairs the body's immune response, they may aggravate the infection by carrying the virus to other parts of the body through the bloodstream.

Source: ACE2-independent infection of T lymphocytes by SARS-CoV-2 | Signal Transduction and Targeted Therapy (nature.com)


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Brain and senses Greg Howard Brain and senses Greg Howard

Damaged nervous system

SARS-CoV-2 can directly infect and reproduce in the cells of the central and peripheral nervous system. The resulting damage may be a cause of brain fog, cognitive and memory problems, dizziness, headaches, and other long-term symptoms that are frequent after Covid infection.

SARS-CoV-2 can directly infect and reproduce in the cells of the central and peripheral nervous system.

The resulting damage may be a cause of brain fog, cognitive and memory problems, dizziness, headaches, and other long-term symptoms that are frequent after Covid infection.

Source: SARS-CoV-2 Infects Peripheral and Central Neurons of Mice Before Viremia, Facilitated by Neuropilin-1 | bioRxiv


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Immune system, Liver and kidneys Greg Howard Immune system, Liver and kidneys Greg Howard

Hepatitis

SARS-CoV-2 may trigger autoimmune processes — T-cells attacking both the virus and the host's own cells — that may be involved in recent cases of hepatitis. Scientists identified mutations in SARS-CoV-2 that cause the virus's proteins to strongly resemble proteins belonging to the host (e.g., infected individuals).

SARS-CoV-2 may trigger autoimmune processes — T-cells attacking both the virus and the host's own cells — that may be involved in recent cases of hepatitis.

Scientists identified mutations in SARS-CoV-2 that cause the virus's proteins to strongly resemble proteins belonging to the host (e.g., infected individuals).

Source: SARS-CoV-2 ORF1abA1061S potentiate autoreactive T cell responses via epitope mimicry: an explanation to hepatitis of unknown cause


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